Postdoctoral Research Fellow in Biomaterials, University of Michigan, Ann Arbor MI, and University of Washington, Seattle WA
Ph.D. in Biomedical Engineering, University of Michigan, Ann Arbor MI
M.S.E in Mechanical Engineering, University of Michigan, Ann Arbor MI
B.S. in Physics and Mathematics, Delaware State University, Dover DE
Kagya Amoako is an expert in device-related infection and cardiovascular and lung assisted medical devices. His research focuses on understanding the mechanisms of artificial materials and blood interaction. In a key finding, he and his team discovered that polymer-bound nitric oxide can inhibit the growth of bacteria and, at the same time, does not damage the viability of surrounding cells.
His work focuses on how to stop the spread of infections associated with implanted medical devices including catheters, pacemakers, stents, vascular grafts, heart valves, artificial lungs, artificial kidneys, and glucose sensors.
With over 200 million implantable devices used in patients in the U.S. alone, and about a four percent infection rate, Dr. AmoakoӰԭs research could impact more than eight million people each year who have device-related infections, improving patient health and reducing hospitalization time and healthcare costs.
As the director of the University of New HavenӰԭs Biomaterials and Medical Device Innovation Laboratory, Dr. Amoako leads teams of graduate students developing new biocompatible surfaces and medical device prototypes and conducting device biocompatibility tests to determine how well the devices would work in clinical practice. His ultimate research goal is to develop the next generation of medical devices that will provide long-term support for cardiovascular and pulmonary disease patients.
In 2017, he published "Achieving Totally Local Anticoagulation on Blood Contacting Devices" in Advanced Materials Interfaces, which examined the challenges of biomaterial surface interaction with blood, biomaterial properties and their influence on coagulation, and old and new surface anticoagulation methods.
His wide-ranging research work includes the development of polymer materials that can be used in the living spaces in spaceships. With support from the NASA Connecticut Space Grant Consortium, Dr. Amoako is developing new surfaces that stop the growth of bacteria in the areas astronauts use daily in space.
He and a student researcher are also developing a prototype of a low-cost prosthetic arm for the more than 2.4 million below-the-elbow amputees who live in developing countries and canӰԭt afford a prosthetic arm.
Dr. Amoako is director of the University of New HavenӰԭs masterӰԭs degree in biomedical engineering, which includes students from the U.S., China, Nigeria, India, Turkey, Iran, and Myanmar. He received his B.S. in physics and mathematics from Delaware State, and his M.S.E. in mechanical engineering and his Ph.D. in biomedical engineering from the University of Michigan.
Surbhi Gupta, KAAmoako, Ahmed Suhaib, Keith E. Cook. Multi-modal, surface focused anticoagulation using poly-2-methoxyethylacrylate polymer grafts and surface nitric oxide release. Advanced Material Interfaces. 2014, doi: 10.1002/admi.201400012
Harihara Sandaram, Xia Han, Ann K. Nowinski, Norman D. Brault, Yuting Li, Jean-Rene Ella- Menye, KAAmoako, Keith E. Cook, Patrick Marek, Kris Senecal, and Shaoyi Jiang. Achieving One-step Surface Coating of Highly Hydrophilic Poly(Carboxybetaine Methacrylate) Polymers on Hydrophobic and Hydrophilic Surfaces. Advanced Materials Interfaces. 2014, doi: 10.1002/admi.201400071
Hitesh Handa, Elizabeth J. Brisbois, Terry C. Major, Lahdan Refahiyat, KAAmoako, Robert H. Bartlett and Mark E. Meyerhof. Hemocompatibility comparison of biomedical grade polymers using rabbit thrombogenicity model for preparing nonthrombogenic nitric oxide releasing surfaces. Journal of materials chemistry. B, Materials for biology and medicine. 2014, 2(8): 1059-1067
Hitesh Handa, Elizabeth J. Brisbois, Terry C. Major, Lahdan Refahiyat, KAAmoako, Gail M. Annich, Robert H. Bartlett and Mark E. Meyerhof. In vitro and in vivo study of sustained nitric oxide release coating using diazeniumdiolate-doped poly(vinyl chloride) matrix with poly(lactide- co-glycolide) additive. Journal of materials chemistry. B, Materials for biology and medicine. 2013,1(29): 3578-3587
KA Amoako, Montoya JP, Major TC, Meyerhof ME, Bartlett RH, Cook KE. Fabrication and In vivo Thrombogenecity Testing of Nitric Oxide Generating Artificial Lungs. J Biomed Mater Res A. 2013, 101(12): 3511-3519
KA Amoako, Archangeli C, Major TC, Meyerhoff ME, Annich GM, Bartlett RH. Thromboresistance Characterization of Extruded Nitric Oxide Releasing Silicone Catheters ASAIO Journal2012; 58: 238 -246
Major TC, Brant DO, Burney CP, KAAmoako, Annich GM, Meyerhoff ME, Handa H, and Bartlett RH. The hemocompatibility of a nitric oxide generating polymer that catalyzes S-nitrosothiol decomposition in an extracorporeal circulation model. Biomaterials2011; 32: 5957e5969
KA Amoako, Cook KE. Nitric oxide-generating silicone as a blood-contacting biomaterial. ASAIO Journal2011; 57:539Ӱԭ544
D. Pokrajac, KAAmoako, Patel H, Brooks J, Cenat N, Marcus K, Darden S. Data Mining in Geosciences. TELSIKS 2003; 534-537
Dr. AmoakoӰԭs teaching interests are in Biomaterials and Design and Application of Biomaterials in Medicine. His teaching philosophy include providing the connection between learning material and the "big picture", treating students with respect, diversifying teaching methods to accommodate both visual and auditory learners, using assessment tools to evaluate teaching methods, and having plans for growth as an educator.
Dr. AmoakoӰԭs research focuses on bio-inspired polymer surface and bulk modification to incorporate anti-clotting functions of the endothelium on biomaterials. His research goal is to address cardiovascular diseases through medical device development. He has worked on medical device fabrication, surface modification, and in vivo testing. Examples of blood contacting devices that he has studied, using animal test models, include artificial lungs and catheters.
The Charger Blog
Whether heӰԭs working to improve artificial lungs or increasing access to ventilators during the pandemic, Kagya Amoako, Ph.D., has been making an important impact in the field of biomedical engineering. Recently inducted into Marquis Who's Who, he is also devoted to providing the Ӱԭbest classroom and laboratory research experienceӰԭ for the next generation of researchers and leaders.
In the Media
Kagya Amoako, associate professor of biomedical engineering and interim chair of mechanical and industrial engineering, has been inducted into Marquis Who's Who for his exemplary expertise in biomedical engineering.
In the Media
Kagya Amoako, associate professor of biomedical engineering, talks about the pause on the Johnson & Johnson vaccine that might cause blood clots in some patients.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments that CVST cases are very rare and may not be related to the Johnson & Johnson vaccine.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments on why it is important to keep wearing a facemask, even after vaccination.
In the Media
Kagya Amoako, associate professor of biomedical engineering, talks about some possible side effects from the COVID vaccine.
In the Media
Dr. Kagya Amoako, associate professor of biomedical engineering, talks about the protective measures taken at the beginning of the lockdown to stop the spread of COVID-19.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments on how to make sure your face mask is working correctly.
In the Media
Kagya Amoako, associate professor of biomedical engineering, discusses concerns that the South African strain has been found in a person in CT who has not traveled.
In the Media
Kagya Amoako, associate professor of biomedical engineering, answers viewers questions live about COVID-19.
In the Media
Kagya Amoako, associate professor of biomedical engineering, talks about the roll out and vaccinations in Connecticut.
In the Media
Kagya Amoako, associate professor of biomedical engineering, discusses the effectiveness of the vaccine as COVID begins to mutate.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments that transparency is the only way another pandemic can be dealt with.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments that the early detection device would have an advantage in combating a viral infection.
In the Media
Kagya Amoako, associate professor of biomedical engineering, comments that the vaccination guideline language needs to be clearer to avoid misunderstandings.
In the Media
Kagya Amoako, associate professor of biomedical engineering, talks about how the rapid test may not be as accurate for determining if you have the coronavirus.
In the Media
Kagya Amoako, associate professor of biomedical engineering, explains how the Pfizer vaccine must be administered within 8 hours of defrosting.
In the Media
Kagya Amoako, associate professor of biomedical engineering, talks about the vaccine having no COVID-19 virus in it.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, talks about vaccine safety for COVID-19.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, talks about each stage of the vaccine process.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, talks about the urgency of following protocols to prevent COVID-19 spreading until everyone can get the vaccine.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, answered viewersӰԭ questions on the coronavirus vaccine.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, says that anyone considering taking the vaccine should talk to a physician.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, talks about when the COVID vaccine may make life return to normal.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, talks about the importance of checking with your doctor about allergic reactions prior to receiving the vaccine.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, comments on how the conclusion of these findings may be important to false-negative testing in COVID-19 patients.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, comments on the importance of wearing a face mask and separating passengers on airlines are meaningful steps to slow the spread of coronavirus.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, comments on the easy fix to a mask that may impede breathing.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, is part of a snapshots of a day in CT feature.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, comments on the effectiveness of steroids in treating COVID-19.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, comments on his research for an artificial lung device amid the ventilator shortage.
In the Media
Kagya Amoako, assistant professor of biomedical engineering, discusses approval for a connector that splits the use of a ventilator made with a 3-D printer he and his students designed.
In the Media
Kagya Amoako, assistant professor, Biomedical Engineering, discusses a splitter he designed for ventilators during the pandemic shortage.
In the Media
Kagya Amoako, assistant professor, Biomedical Engineering, discusses a splitter he designed and is awaiting FDA Emergency approval to be deployed.
University News
Dr. Kagya Amoako and his students are using 3D-printing technology to develop innovative solutions for the possible lack of critical equipment healthcare providers need to treat patients impacted by the global COVID-19 pandemic.