Nathan Seifert, Ph.D.
Chemistry and Chemical & Biomedical Engineering Department
Tagliatela College of Engineering
Education
Ph.D., Physical Chemistry, University of Virginia
B.A., Chemistry, Amherst College
About Nathan
Nathan Seifert joined the faculty of the University of New Haven in August 2021. His research interests since graduate school have focused on the development of chirped pulse Fourier transform microwave (CP-FTMW) spectroscopic techniques, and applications of CP-FTMW spectroscopy for both physical chemistry and analytical applications. Though much of his previous research has been on the experimental aspects of molecular spectroscopy, Nathan has a strong interest in applying data science and machine learning techniques for the automated interpretation of molecular spectra in analytical chemistry and structure determination.
NathanӰԭs research at the University of New Haven going forward will center on development of a low-cost CP-FTMW spectrometer for structure determination and chemical mixture analysis, and the development of software and machine learning techniques for digital signal processing, spectral assignment, structure elucidation, and novel improvements to the software-hardware instrument interface.
Selected Publications
D. P. Zaleski, R. Sivaramakrishnan, H. R. Weller, N. A. Seifert, D. H. Bross, B. Ruscic, K. B. Moore III, S. N. Elliott, A. V. Copan, L. B. Harding, S. J. Klippenstein, R. W. Field, K. Prozument, ӰԭSubstitution Reactions in the Pyrolysis of Acetone Revealed through a Modeling, Experiment, Theory Paradigm,Ӱԭ J. Am. Chem. Soc. 2021, 143, 3124-3142.
F. Xie, N. A. Seifert, W. Jäger, Y. Xu, ӰԭConformational Panorama and Chirality Controlled StructureӰԭEnergy Relationship in a Chiral Carboxylic Acid Dimer,Ӱԭ Angew. Chem. Int. Ed. 2020, 59, 15703-15710.
3) N. A. Seifert, A. S. Hazrah, W. Jäger, ӰԭThe 1-Naphthol Dimer and Its Surprising Preference for πӰԭπ Stacking over Hydrogen Bonding,Ӱԭ J. Phys. Chem. Lett. 2019, 10, 2836-2841.
S. Oswald, N. A. Seifert, F. Bohle, M. Gawrilow, S. Grimme, W. Jäger, Y. Xu, M. A. Suhm, ӰԭThe Chiral Trimer and a Metastable Chiral Dimer of Achiral Hexafluoroisopropanol: A MultiӰԭMessenger Study,Ӱԭ Angew. Chem. Int. Ed. 2019, 131, 5134
N. A. Seifert, J. Thomas, W. Jäger, Y. Xu, ӰԭRotational spectra and theoretical study of tetramers and trimers of 2-fluoroethanol: dramatic intermolecular compensation for intramolecular instability,Ӱԭ Phys. Chem. Chem. Phys. 2018, 20, 27630-27637.
J. Thomas, N. A. Seifert, W. Jäger, Y. Xu, ӰԭA Direct Link from the Gas to the Condensed Phase: A Rotational Spectroscopic Study of 2, 2, 2ӰԭTrifluoroethanol Trimers,Ӱԭ Angew. Chem. Int. Ed. 2017, 129, 6386-6390.
N. A. Seifert, I. A. Finneran, C. Pérez, D. P. Zaleski, J. L. Neill, A. L. Steber, R. D. Suenram, A. Lesarri, S. T. Shipman, B. H. Pate, ӰԭAUTOFIT, an automated fitting tool for broadband rotational spectra, and applications to 1-hexanal,Ӱԭ J. Mol. Spectrosc. 2015, 312, 13-21.
C. Pérez, D. P. Zaleski, N. A. Seifert, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, ӰԭHydrogen Bond Cooperativity and the ThreeӰԭDimensional Structures of Water Nonamers and Decamers,Ӱԭ Angew. Chem. Int. Ed. 2014, 126, 14596-14600
C. Pérez, S. Lobsiger, N. A. Seifert, D. P. Zaleski, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, ӰԭBroadband Fourier transform rotational spectroscopy for structure determination: The water heptamer,Ӱԭ Chem. Phys. Lett. 2013, 571, 1-15.
C. Pérez, M. T. Muckle, D. P. Zaleski, N. A. Seifert, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, ӰԭStructures of cage, prism, and book isomers of water hexamer from broadband rotational spectroscopy,Ӱԭ Science 2012, 336, 897-901.
Full publication list can be found at